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Biology & Bioinformatics Examples

Natural language prompts for biological modeling and data analysis.

Systems Biology

Model a gene regulatory network with feedback loops

Simulate the cell cycle with checkpoints

Model metabolic flux through glycolysis

Simulate the lac operon switching behavior

Model calcium signaling in a cell

Analyze the stability of a genetic toggle switch

Simulate circadian rhythm oscillations

Model signal transduction cascades

Analyze the robustness of a biological network

Simulate cell fate decisions in development

Population Dynamics

Model predator-prey dynamics with carrying capacity

Simulate the spread of an invasive species

Model competition between two species

Analyze metapopulation dynamics with migration

Simulate age-structured population growth

Model disease spread with vaccination

Analyze evolutionary game theory dynamics

Simulate genetic drift in a small population

Model fishery dynamics with harvesting

Analyze the Allee effect on population persistence

Evolutionary Biology

Simulate natural selection on a quantitative trait

Model the evolution of antibiotic resistance

Simulate speciation with geographic isolation

Model coevolution between host and parasite

Analyze phylogenetic trees using molecular clocks

Simulate neutral evolution and genetic drift

Model the evolution of cooperation using game theory

Analyze selective sweeps in genomic data

Simulate adaptive radiation on an island

Model the evolution of sexual reproduction

Molecular Biology

Simulate DNA replication with error rates

Model protein folding energy landscape

Analyze codon usage bias in a genome

Simulate mRNA translation with ribosome dynamics

Model gene expression noise

Analyze protein-protein interaction networks

Simulate CRISPR-Cas9 editing efficiency

Model epigenetic inheritance patterns

Analyze alternative splicing patterns

Simulate viral replication dynamics

Bioinformatics

Align two DNA sequences using Smith-Waterman

Build a phylogenetic tree from multiple sequences

Predict protein secondary structure

Cluster gene expression data

Identify differentially expressed genes

Analyze SNP associations with phenotype

Predict transcription factor binding sites

Build a hidden Markov model for gene finding

Analyze RNA-seq read counts

Predict protein function from sequence

Neuroscience

Simulate a network of integrate-and-fire neurons

Model synaptic plasticity with STDP

Analyze spike train correlations

Simulate the visual cortex orientation selectivity

Model working memory in a recurrent network

Analyze EEG power spectra and coherence

Simulate dopamine signaling and reward

Model decision making with drift-diffusion

Analyze fMRI connectivity patterns

Simulate epileptic seizure dynamics

Ecology

Model ecosystem dynamics with multiple trophic levels

Simulate forest fire spread

Analyze species-area relationships

Model nutrient cycling in an ecosystem

Simulate climate effects on species distribution

Analyze food web stability

Model the carbon cycle

Simulate coral reef dynamics

Analyze biodiversity indices

Model pollination network dynamics

Physiology

Model cardiac electrophysiology

Simulate kidney filtration and reabsorption

Model lung gas exchange

Simulate muscle contraction dynamics

Model hormone feedback loops

Analyze heart rate variability

Simulate the baroreceptor reflex

Model thermoregulation

Analyze respiratory mechanics

Simulate the pupillary light reflex

Epidemiology

Model COVID-19 spread with interventions

Simulate endemic disease equilibrium

Analyze contact tracing effectiveness

Model vaccine distribution strategies

Simulate superspreading events

Analyze the basic reproduction number R0

Model hospital capacity during outbreak

Simulate quarantine effectiveness

Analyze age-structured disease dynamics

Model vector-borne disease transmission

Biomechanics

Analyze gait kinematics and kinetics

Model muscle force generation

Simulate bone remodeling under load

Analyze joint reaction forces

Model blood flow through heart valves

Simulate cell migration mechanics

Analyze sports biomechanics

Model wound healing mechanics

Simulate cartilage loading

Analyze swimming or flying locomotion

Structural Biology

Predict protein structure from sequence

Analyze protein dynamics with normal modes

Model ligand binding affinity

Simulate membrane protein insertion

Analyze allosteric communication pathways

Model protein aggregation

Simulate DNA-protein interactions

Analyze cryo-EM density maps

Model enzyme catalytic mechanisms

Simulate molecular crowding effects

Synthetic Biology

Design a genetic oscillator circuit

Model a biosensor response curve

Optimize codon usage for expression

Design a genetic logic gate

Model metabolic pathway optimization

Simulate cell-free expression systems

Design a kill switch for biocontainment

Model directed evolution outcomes

Simulate a synthetic minimal cell

Design orthogonal genetic systems